23484.rar Link

: Show that mice unable to form the PKG disulfide bond (C42S KI) exhibit different blood pressure responses compared to wild-type (WT) mice.

: Protein Kinase G Iα (PKG Iα) is usually activated by cGMP, but it can also be activated by "oxidative stress" (specifically the formation of a disulfide bond at Cys42). 23484.rar

Are you writing this for a or a journal submission ? : Show that mice unable to form the

: To prove that preventing or reversing this oxidative activation can lower blood pressure. 3. Methods (Key Techniques) 23484.rar