If this is the scientific context you are looking for, the primary features related to this data include:

: It examines the ability of the mutant proteins to exchange nuclear co-repressors for co-activators, which is a critical factor in how the body responds—or fails to respond—to therapy.

: This specific data (prot.24010) details the molecular consequences of resistance to All-Trans Retinoic Acid (ATRA) , a standard treatment for APL. RAR