The study investigates the role of specific proteins, including CaMKII (Calmodulin-dependent protein kinase II) and actinin , in managing the structural integrity and growth of the dendritic spine.

Download links * Insight. * Structural Biology and Molecular Biophysics. * CaMKII. * actinin. * long-term potentiation. * synapse.

Supplemental information, including data sets and molecular models, is also available for download on the same page. Synapses: Changing the size of dendritic spines - eLife

The research highlights how the spine's physical volume adapts in response to neural activity, specifically focusing on the biochemical signaling that triggers these expansions. 3. Significance

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Changes in spine size are closely linked to LTP, a process that strengthens synapses over time.

Mechanisms of Synaptic Strength and Spine Size Regulation Reference: eLife 2023;12:e91566 1. Overview

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