Are you more interested in the lore, or were you referring to a specific storyline from the Syfy television series ?

: In a cruel twist of fate, Van Helsing (as a werewolf) kills Dracula but also accidentally kills Anna just as she administers the cure.

: Characters like Sam (the serial killer turned vampire) represent the "broken" psyche of those who have lost their humanity entirely.

: The episode focuses on the fallout between Axel and Vanessa after the death of Scarlett.